Datasets (31,150)

Cystic fibrosis (CF) is the most common lethal genetic disease, caused by CFTR (cystic fibrosis transmembrane conductance regulator) gene mutations. CF is characterized by an ionic imbalance and thickened mucus, leading to impaired mucociliary clearance and promoting bacterial colonization and the establishment of infection/inflammation cycles. However, the origin of this inflammation remains unclear. The goal of this study was to investigate the differential expression of mRNA in CF patients to determine new therapeutic strategy.

RNA-seq to investigate impact of treatment of KRAS mutant NCI-H2009 lung adenocarcinoma cells with the multi-ERBB inhibitor Neratinib

RNA-seq to investigate impact of treatment of KRAS mutant NCI-H358 lung adenocarcinoma cells with the multi-ERBB inhibitor Neratinib

RNA-seq to investigate impact of treatment of KRAS mutant A549 lung adenocarcinoma cells with the multi-ERBB inhibitor Neratinib

Telomere length and telomerase activity in T-cells are biomarkers of high performing centenarians

RNA-Seq of 293T cells depleted of U2AF-related proteins

Gene activation precedes DNA demethylation in response to infection in human dendritic cells

KDM5 histone demethylases repress innate immune response via suppression of STING

Transcriptome analysis to investigate the role of EDC3 in a neuronal cell line

Homo sapiens Raw sequence reads

Incomplete penetrance for isolated congenital asplenia in humans with mutations in translated and untranslated RPSA exons

Global transcriptome analysis of BJAB cells that are modulated by EBV infection or (and) EBV BART6-3p mimics.

Ribosome profiling of G2019S LRRK2 human dopamine neurons

Propargite, an environmental chemical, interacts with GWAS identified diabetes genes to impact human pancreatic ß-cell death [PTPN2 knockout]

Propargite, an environmental chemical, interacts with GWAS identified diabetes genes to impact human pancreatic ß-cell death [propargite treatment]