Public Data
11 samples
Targeting Integrated Stress Response by ISRIB combined with Imatinib attenuates STAT5 signaling and eradicates therapy-resistant Chronic Myeloid Leukemia cells
Accession: SRP314364
Published: 2022
xenograft
compound, control
chronic myelogenous leukemia, BCR-ABL1 positive
Public Data
6 samples
MLL3 loss drives metastasis and therapeutic resistance by promoting a hybrid EMT state [RNA-seq]
Accession: SRP313393
Published: 2022 in Nat Cell Biol
cell line
compound
breast
breast cancer
Public Data
35 samples
Dual T cell– and B cell–intrinsic deficiency in humans [CD4+ T cell SubSeries]
Accession: SRP312190
Published: 2022
primary cells
compound, control, ...
blood
normal
Public Data
42 samples
RNAseq analysis of A549 and THP1 cells infected with H3N2 influenza A virus
Accession: SRP311617
Published: 2022
cell line, other
control, infection
blood, lung
childhood acute myeloid leukemia, lung adenocarcinoma
Public Data
70 samples
ACKR3 promotes CXCL12/CXCR4-mediated migration of lymphoma cells
Accession: SRP311195
Published: 2022 in Front Immunol
cell line
compound, crispr
bone marrow, pleural effusion
diffuse large B-cell lymphoma, lymphoma
Public Data
10 samples
Mesenchymal stromal cells improve the transplantation outcome of CRISPR-Cas9 gene-edited human HSPCs (RNA-seq)
Accession: SRP310452
Published: 2022 in Mol Ther
other, primary cells
control, crispr
bone marrow, mesenchymal cell
Public Data
9 samples
Topoisomerase 1 dependent R-loop deficiency drives accelerated replication and genomic instability
Accession: SRP310281
Published: 2022 in Cell Rep
cell line
control, overexpression, ...
skin of prepuce of penis
Public Data
12 samples
DNA Replication Stress Generates Distinctive landscapes of DNA copy number alterations and chromosome scale losses
Accession: SRP310178
Published: 2022 in Genome Biol
cell line
compound, control
eye, retina, ...
Public Data
12 samples
Mitochondrial double-stranded RNAs as a pivotal mediator in the pathogenesis of Sjogren's syndrome
Accession: SRP309081
Published: 2022 in Mol Ther Nucleic Acids
cell line
compound, compound, ...
saliva-secreting gland
Public Data
9 samples
Loss of the chromatin remodeler, ATRX, promotes aggressive features of osteosarcomas and activates NF-kB signaling and integrin receptor binding
Accession: SRP308220
Published: 2022 in JCI Insight
cell line
control, shrna
bone cell
osteosarcoma
Public Data
8 samples
MYO10-filopodia support basement membranes at pre-invasive tumor boundaries
Accession: SRP306743
Published: 2022 in Dev Cell
xenograft
control, shrna
breast
breast cancer
Public Data
24 samples
The AhR-SRC axis as a therapeutic vulnerability in BRAFi-resistant melanoma
Accession: SRP305866
Published: 2022 in EMBO Mol Med
cell line
compound, control, ...
zone of skin
melanoma
Public Data
6 samples
Quantitative Analysis of Transcriptomes of small molecules generated Neural Precursor Cesll (smNPCs) and smNPCs-derived neurons by next generation sequencing
Accession: SRP305499
Published: 2022
primary cells
blood
Public Data
4 samples
The protein kinase activity of NME7 activates one-carbon metabolism through positively regulating wnt/ß-catenin signaling
Accession: SRP304271
Published: 2022
cell line
compound, shrna, ...
liver
hepatocellular carcinoma
Public Data
4 samples
Metastasis-repressive CircRNA MASCOT Regulates Distribution of the Splicing Factor hnRNP M
Accession: SRP303358
Published: 2022 in Nat Commun
cell line
compound, control
breast