Datasets (28,470)

eIF1 modulates the recognition of sub-optimal translation start sites and steers gene expression control mediated by uORFs

Adaptive chromatin remodeling in glioblastoma stem cell plasticity and drug tolerance

Activation of a SOX2-dependent transcriptional regulatory circuit drives glioblastoma.

Enhancer Remodeling During Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacological Targeting of the P-TEFb Complex (RNA-seq)

Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival [RNA-Seq]

MGN1703 induces type I interferon in the colon

A Quantitative Mammalian Atlas of A-to-I RNA Editing

Reduced mitochondrial activity in colonocytes facilitates AMPKa2-dependent inflammation

iPSCs Reveal Protective Modifiers of the BMPR2 mutation in Pulmonary Arterial Hypertension

We generated a mouse model that allows conditional knock-out of the NADPH-P450 oxidoreductase (Por) gene, which is the only electron donor for all murine cytochromes and embryonic-lethal when deleted1. We introduced additional deletions in the conditional Porc/c mouse to generate a PIRF (Porc/c /Il2rg-/- /Rag2-/-/Fah-/-) strain. These data compare expression profiles in the resulting tissues.

Next Generation Sequencing Analysis of control and SRSF2-/- Huh7 cells Transcriptomes

Modulation of microRNA-mRNA Target Pairs by Human Papillomavirus 16 Oncoproteins

An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [polyA RNA-seq]

An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq]

Gene expression analysis of human spinal motor neurons (MN) differentiated from ALS patient derived iPSC